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Tadarise is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum. This then activates the enzyme guanylate cyclase, which increases cyclic guanosine monophosphate (cGMP) levels, leading to smooth muscle relaxation in the corpus cavernosum, resulting in an increased inflow of blood and an erection .
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